A.M. Brufsky, M. Mayer, H.S. Rugo, M. Ulcickas Yood, P.A. Kaufman, E. Tan-Chiu, D. Tripathy, M. Birkner, L. Wang,
M.G. Brammer, D.A. Yardley RegistHER: Patient Characteristics and Time Course of Central Nervous System Metastases in Patients with HER2+ Metastatic Breast Cancer. ASCO Breast Cancer 2008 Sept 5-7.
Heyn, C., Ronald, J.A., Ramadan, S. S., MacKenzie, L.T., Mikulis, D.J., Palmieri, D., Bronder, J.L., Steeg, P.S., Yoneda, T., MacDonald, I.C., Chambers, A.F., Rutt, B.K. and Foster, P.J.: In vivo tracking of growth and dormancy of solitary cells in a mouse model of breast cancer metastasis to the brain using MRI. Mag. Reson. Med. 56: 1001-1010, 2006.
Mayer, M.: A patient perspective on brain metastases in breast cancer. Clin. Cancer Res. 13: 1623-1624, 2007.
Muldoon LL, Soussain C, Jahnke K, Johanson C, Siegal T, Smith QR, Hall WA, Hynynen K, Senter PD, Peereboom DM, Neuwelt EA: Chemotherapy delivery issues in central nervous system malignancy: a reality check. J Clin Oncol. 25(16):2295-305, 2007.
Palmieri, D., Smith, Q.R., Lockman, P.R., Bronder, J.L., Gril, B., Ahmad, A., Chambers, A.F., Weil, R. J. and Steeg, P.S.: Brain metastasis of breast cancer. Breast Diseases. 26:139-147, 2007.
Palmieri, D., Chambers, A.F., Felding-Haberman, B., Huang, S. and Steeg, P.S.: The biology of metastasis to a sanctuary site. Clin. Cancer Res. 13: 1656-1662, 2007.
Palmieri, D., Bronder, J.L., Herring, J.M., Yoneda, T., Weil, R.J., Stark, A.M., Kurek, R., Vega-Valle, E., Feigenbaum, L., Vortmeyer, A.O., Aldape, K. and Steeg, P.S.: Her-2 overexpression increases the metastatic outgrowth of breast cancer cells in the brain. Cancer Res. 67:4190-4198, 2007.
Abstracts
Brogi, E., Murray, M.P., Nehhozina, T., Akram, M., Cranor, M., Seidman, A. Clinical and pathologic characteristics of brain metastases of breast carcinoma: A study of 74 patients. San Antonio Breast Cancer Symposium, San Antonio, TX. 2006.
Fitzgerald Daniel, Palmieri Diane, Vega-Valle, Jeanne Herring, Steeg Patricia. A xenograft model of brain metastasis of breast cancer: metastatic tumors and the brain microenvironment. American Association of Cancer Research Annual Meeting.Los Angeles, CA. 2007
Gril Brunhilde, Palmieri Diane, Elezar Vega-Valle, Hua k., Herring Jeanne, Gilmer Tona, Rubin Stephen, Steeg Patricia. Lapatinib Prevents the Metastatic Colonization of EGFR+ and Her-2+ Breast Cancer Cells in the Brain. American Association of Cancer Research Annual Meeting. Los Angeles, CA. 2007.
Heyn C, Ronald JA, Ramadan SS, Snir JA, Barry AM, MacKenzie LT, Mikulis DJ, Palmieri D, Bronder JL, Steeg PS, Yoneda T, MacDonald IC, Chambers AF, Rutt BK, Foster PJ. In vivo tracking of growth and dormancy of solitary cells in a mouse model of breast cancer metastasis to brain using MRI. 14th Scientific Meeting & Exhibition of the International Society for Magnetic Resonance in Medicine, Seattle,WA. 2006.
Hunt Mathew, Muldoon Leslie, Palmieri Diane, Steeg Patricia, Neuwelt Edward. “HER-2 status influences survival in a rat model of brain metastasis from breast cancer”. Annual Blood-Brain Barrier Consortium Meeting. Skamania Lodge, WA. 2007.And American Association of Cancer Research Annual Meeting. Los Angeles, CA. 2007.
Mittapalli RK, Manda VK, Smith QR and Lockman PR. Permeability of the fluorophore Texas red is not subject to MRP-2 mediated efflux at the blood-brain barrier. The American Association of Pharmaceutical Scientists, Annual Meeting. San Diego, CA. 2007.
Mittapalli RK, Fitzgerald A, Manda VK and Lockman PR. A computational approach to predict the blood-brain permeability of fluorescent dyes. The American Association of Pharmaceutical Scientists, Annual Meeting. San Diego, CA. 2007.
Newsham Irene and Price Janet. Dissecting the extravasation process of metastatic breast cancer cells using an Electric Cell- Substrate Impedance Sensing (ECIS) assay. Metastasis Research Society Meeting, 2006.
Palmieri Diane, Bronder Julie, J. Weil Robert, Stark Andreas, Davis Sean, Vega-Valle Eleazar, Herring Jeane, Toshiyuki Yoneda, Kurek Raffael, Mehdorn H., Meltzer Paul, Steeg Patricia. Preclinical studies in support of the use of Vorinostat (SAHA) for the treatment of brain metastases of breast cancer. American Association of Cancer Research Annual Meeting. Los Angeles, CA. 2007
Ramadan S, Heyn C, Rutt B, Foster P. Single cell MRI with FIESTA:quantitative benefits of 3T vs. 1.5T. 14th Scientific Meeting & Exhibition of the International Society for Magnetic Resonance in Medicine, Seattle, WA. 2006.
Ramadan S, MacKenzie L, Steeg P, Palmieri D, Chambers A, Rutt B, Foster P. In-vivo MR tracking of solitary cells as a tool for comparing the metastatic behaviour of two distinct breast cancer cell lines. Imaging Network Ontario 6th Imaging Symposium, Toronto, ON, Canada. 2007.
Ramadan SS, MacKenzie LT, Steeg PS, Chambers AF, Rutt BK, Foster PJ. In vivo tracking of solitary cells as a tool for comparing the behaviour of two metastatically-distinct cell lines in a mouse model of breast cancer metastasis to the brain. 15th Scientific Meeting & Exhibition of the International Society for Magnetic Resonance in Medicine, Berlin, Germany. 2007.
Rudraraju Thomas V, Lockman PR, and Smith QR. Blood brain barrier permeability and transport of temozolomide. The American Association of Pharmaceutical Scientists, Annual Meeting. San Diego, CA. 2007.
Taskar K, Mittapalli RK, Rudraraju V, Egbert JA, Bohn KA, Gaasch JA, Thomas F, Lockman PR and Smith QR. Improved Left Ventricle Intracardiac injection method for brain metastases of breast cancer in immune compromised mice. Society for Neuroscience Annual Meeting. San Diego, CA. 2007
Presentations
Chambers Ann, “Dormancy and Growth of Tumor Cells in Ectopic Sites”. Invited speaker, Educational Session on ‘Invasion and Metastasis’. American Association for Cancer Research 97th Annual Meeting, Washington, DC, April 2006.
Chambers Ann, “Biology of Tumor Metastasis and Clinical Implications”. Invited speaker, McGill Cancer Group Seminar Series, McGill University, Montreal, Quebec, Canada, April 2006.
Chambers Ann, “Tumor Metastasis: Mouse Models and Preclinical Imaging”. Invited speaker, Lawson Imaging Seminar Series, London, Ontario, Canada. April 2006.
Chambers Ann, “Breast Cancer Metastasis”. Invited speaker, EMBO Conference on Common Molecular Mechanisms of Mammary Gland Development and Breast Cancer Progression. Dublin, Ireland. June 2006.
Ann Chambers, “Imaging the metastatic process in experimental models and clinical simplications”. Invited workshop participant, National Cancer Institutes, NIH, ‘Tumor Dormancy Workshop’. Bethesda, MD. July 2006.
Chambers Ann, “Imaging the Metastatic Process: Preclinical Models and Clinical Implications”. Invited speaker, Usha Mahajani Symposium on Cancer Biology, University of California San Diego/Salk Institute, La Jolla, CA, September 2006.
Chambers Ann, “Imaging the Metatatic Process in Experimental Models and Clinical Implications”. Invited Speaker, Ben May Institute for Cancer Research, University of Chicago. Cancer Research Symposium on Frontiers in Metastasis Research, Chicago, October 2006.
Chambers Ann, “Biology of Breast Cancer Metastasis”. Invited speaker/faculty, 7th Annual New Strategies in Breast Cancer Conference. Philadelphia, PA. April 2007.
Chambers Ann, “Host factors in tumor dormancy”. Invited speaker, 1st Annual Columbus Breast Cancer Symposium. Columbus, OH. April 2007.
Chambers Ann, “Imaging tumor metastasis and dormancy in experimental models”. Invited speaker, Second International Symposium on Cancer Metastasis and the Lymphovascular System, San Francisco, CA. May 2007.
Chambers Ann and Nathanson David, “Animal models to study lymphatic and vascular metastasis”. Meet-the-Professor Breakfast, Second International Symposium on Cancer Metastasis and the Lymphovascular System, San Francisco, CA. May 2007.
Chambers Ann, “Novel imaging approaches for studying tumor metastasis”. Invited participant, Fondation IPSEN annual meeting on Cancer Science, Metastasis and Invasion. Cancer think-tank. Abazzia de Spineto, Tuscany, Italy. May 2007.
Lockman Paul, “Drug delivery across the blood-tumor barrier.” Invited Seminar, The University of Texas, MD. Anderson Cancer Center, Cancer Biology Seminar Series. Houston, Tx. February, 2007.
Lockman Paul, “Permeability at the blood-tumor barrier.” Invited Seminar, Northeastern Ohio University, Colleges of Medicine, Akron, Ohio. 2007.
Neuwelt Edward, “Immunotherapy in Brain Tumors: Preclinical and Clinical Studies” Presented at the annual Blood-Brain Barrier Consortium meeting. Skamania, WA. 2007.
Neuwelt Edward, “Mechanisms of Disease: The Blood-Brain Barrier and CNS Tumors” Henry Ford Hospital, Detroit MI. 2006.Copyright BrainMetsBC.orglogo
Smith Quentin, “Tumors and the Blood-Brain Barrier” 13th Annual Blood-Brain Barrier Consortium Meeting. Sevenson, WA. March 2007.
Smith Quentin, “Brain Drug Delivery through Carrier-Mediated Transport” 18th Annual Spring Brain Conference. Sedona, Arizona.
Patricia Steeg, “A molecular portrait of breast cancer metastasis to the brain”. Ruth Sager Memorial Lecture, Boston Cancer Research Association. April 2007.
Steeg Patricia, “Brain metastases of breast cancer”. Keynote speaker, Ben May Institute for Cancer Research, University of Chicago. Cancer Research Symposium on Frontiers in Metastasis Research. October 2006.
Steeg Patricia, “The role of Her-2 in brain metastasis”. Invited speaker, BRESCOM Breast cancer and metastasis conference. Paris, France. June 2006.
Steeg Patricia, “New molecular targets for metastatic breast cancer”. Invited speaker, Metastatic Breast Cancer Network, New York, NY. October 2006.
