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Conventional Surgery, Radiosurgery (Stereotactic) and Whole Brain Radiation

B. Atalar et al  Risk of Leptomeningeal Disease in Patients Treated with Stereotactic Radiosurgery Targeting the Postoperative Resection Cavity for Brain Metastases Int J Radiat Oncol Biol Phys 2013 Nov 15;713-8

A. Cole et al  Self-Reported Cognitive Outcomes in Patients with Brain Metastases Before and After Radiation Therapy  Int J Radiat Oncol Biol Phys  2013 Nov 15;87(4):705-12

G. Truc et al  What Place for the Whole-Brain Radiotherapy with Hippocampal Sparing? Cancer Radiother 2013 Oct;17(5-6):419-23 (Article in French)

G. Minniti et al  Multidose Stereotactic Radiosurgery (9Gy x3) of the Postoperative Resection Cavity for Treatment of Large Brain Metastases   Int J Radiat Oncol Biol Phys 2013 July15 86(4):623-9 

P. Rava et al  Survival Among Patients with 10 or More Brain Metastases Treated with Stereotactic Radiosurgery  J Neurosurg 2013 Aug;119(2):457-62

H. Jung et al   Managing Brain Metastases Patients With and Without Radiotherapy: Initial Lessons from a Team-Based Consult Service Through a Multidisciplinary Integrated Palliative Oncology  Clinic Support Care Cancer 2013 Aug 10

S. Yomo et al  The Efficacy and Limitations of Stereotactic Radiosurgery as a Salvage Treatment After Failed Whole Brain Radiotherapy for Brain Metastases  JNeurooncol  2013 Jul;113(3):459-65

F. Hsu  Population-Based Outcomes of Boost Versus Salvage Radiosurgery for Brain Metastases After Whole Brain Radiotherapy  Radiother Oncol 2013 Jul;108(1):128-31

D. Salvetti et al  Gamma Knife Surgery for the Treatment of 5 to 15 Metastases to the Brain: Clinical Article  J Neurosurg 2013 Jun;118(6):1250-7

B. Lippitz et al  Stereotactic Radiosurgery in the Treatment of Brain Metastases: The Current Evidence  Cancer Treat Rev 2013 Jun 26 (Epub ahead of print)

J. Jabboin et al  Survival Following Gamma Knife Radiosurgery for Brain Metastasis from Breast Cancer  Radiat Oncol 2013 May 29;8(1):131

M. Yamamoto et al  A Case-Matched Study of Stereotactic Radiosurgery for Patients with Multiple Brain Metastases: Comparing Treatment Results for 1-4 vs 5 Tumors or More: Clinical Article JNeurosurg 2013;118(6):1258-68

M. Sengoz et al  Treatment of Brainstem Metastases with Gamma-Knife Radiosurgery  J Neurooncol 2013 May;113(1):33-8

T. Kawabe et al  Gamma Knife Surgery for Patients with Brainstem Metastases  SJ Neurosurg 2012 Dec;117 Suppl:13-6

T. Vern-Gross Breast Cancer Subtype Affects Patterns of Failure of Brain Metastases after Treatment with Stereotactic Radiosurgery  J Neurooncol 2012 Dec;110(3):381-8  

M. Tsao et al  Whole Brain Radiotherapy for the Treatment of Newly Diagnosed Multiple Brain Metastases  Cochrane Database Syst Rev 2012 April 18 4

M. Yamamoto et al   How Many Metastases Can be Treated with Radiosurgery   Prog Neurol Surg. Kim and Lunsford (eds) Current and Future Management of Brain Metastasis Basel, Karger 2012 vol 25: 261-272

D. Rades et al   Resection Plus Whole-Brain Irradiation Versus Resection Plus Whole-Brain Irradiation Plus Boost for the Treatment of Single Brain Metastasis   Strahlentherapie und Onkologie  2012 188:143-147

CC. Wang   Cyberknife Hypofractionated Stereotactic Radiosurgery (HSRS) of Resection Cavity after Excision of Large Cerebral metastasis: Efficacy and Safety of an 800 cGy x 3 Daily Fractions Regimen  Journal of Neurooncology  (2012) 106:601-610

Z. Xu et al   Impact of Preexisting Tumor Necrosis on the Efficacy of Stereotactic Radiosurgery in the Treatment of Brain Metastases in Women With Breast Cancer Cancer 2012 118:1323-33

J. Ebinu et al   Gamma Knife Radiosurgery for the Treatment of Cystic Cerebral Metastases   International Journal of Radiation Oncology Biology Physics Aug 9  2012

P. Kelly et al Linear Accelerator-Based Stereotatic Radiosurgery for Brainstem Metases, the Dana-Farber/Brigham and Women's Center Experience Journal of Neuroocology Sept 2011 104(2):553-7

D. Rades et al Shorter-Course Whole-Brain Radiotherapy for Brain Metastases in Elderly International Journal of Radiation Oncology Biology Physics Apr 6 2011

L. Horky et al Dual Phase FDG-Pet Imaging of Brain Metastases Provides Superior Assessment of Recurrence Versus Post-Treatment Necrosis Journal of Neurooncology May 2011 103(1):137-46

H. Yang et al What Factors predict the Responses of Larger Brain Metastases to Radiosurgery Neurosurgery March 2011 68(3):682-9

D. Kondziolka et al Stereotactic Radiosurgery as Primary and Salvage Treatment for Brain Metastases from Breast Cancer Journal of Neurosurgery March 2011 14(3):792-800

S. Matsunaga et al Gamma Knife Surgery for Metastatic Brian Tumors from Primary Breast Cancer Treatment Indication Based on Numbers of Tumors and Breast Cancer Phenotype Journal of Neurology Dec 2010 113Suppl:65-72

T. Serizawa et al Gamma Knife Surgery for Sole Treatment for Multiple Brain Metastases: 2-Center Retrospetive Review of 1508 Cases Meeting the Inclusion Criteria of the JLGK0901 Multi-Institution Prospective Study Journal of Neurology Dec 2010 113Suppl:48-52

N. Dea et al Safety and Efficacy of Gamma Knife Surgery for Brain Metastases in Eloquent Locations Journal of Neurosurgery Dec 2010 113 Suppl:79-83

H. Woo et al Factors Related to the Local Treatment Failure of Gamma Knife Surgery for Metastatic Brain Tumors Acta Neurochir (Wien) Nov 2010 152(110):1909-14

A. Della Puppa et al Solitary Intra-Ventricular Brain Metastasis from a Breast Carcinoma Journal of Neurooncology March 2010 97(1):123-6

C. Patil et al Whole Brain Radiation Therapy (WBRT) alone versus WBRT and Radiosurgery for the Treatment of Brain Metastases Cochrane Collaboration 2010

K. Komosinska et al Prospective Evaluation of the Palliative Effect of Whole-Brain Radiotherapy in Patients with Brain Metastases and Poor Performance Status Acta Oncologica 2010(44)382-388 (free full text)

J. Marsh et al Intracranial Metastatic Disease Spares The Limbic Circuit: A Review of 697 Metastatic Lesions in 107 Patients International Journal of Radiation Oncology Biology Physics 2010 (76) 2:504-512

N. Marko and R Weill Neurocognitive Considerations in the Treatment of Brain Metastases Nature Reviews Clinical Oncology April 2010 (7)185-186 (free full text)

 Chargari et al  Whole-Brain Radiation Therapy in Breast Cancer Patients with Brain Metastases National Reviews Clinical Oncology Jul 13 2010

J. S. Gripp et al  Palliative Radiotherapy Tailored to Life Expectancy in end-Stage Cancer Patients: Reality or Myth? Cancer Jul 1 2010 116(13) 3251-6

C. Valery et al  Minimized Doses for Linear Accelerator Radiosurgery of Brainstem Metastasis  International Journal of Radiation Oncology Biology Physics  June 30 2010

A. Niwinska et al  Breast Cancer Subtypes and Response to Systemic Treatment after Whole-Brain Radiotherapy in Patients with Brain Metastases. Cancer 2010 June 14

H. Aoyama  Radiation Therapy for Brain Metastases in Breast Cancer Patients  Breast Cancer, May 11 2010

K. Kominska et al  Prospective Evaluation of the Palliative Effect of Whole-Brain Radiotherapy in Patients with Brain Metastases and Poor Performance Status  Act Oncol Apr 2010 49(3):382-88

E Chang et al Neurocognition in Patients with Brain Metastases Treated with Radiosurgery plus Radiosurgery or Radiosurgery plus Whole-Brain Radiosurgery Irradiation: A Randomized Controlled Trial Lancet Oncology 2009 (10)1037-1044 (free full text)

D Rades et al Whole Brain Radiotherapy Plus Stereotactic Radiosurgery versus Surgery Plus Whole Brain Radiotherpay for 1-3 Brain Metastases: Results of a Matched Pair Analysis European Journal of Cancer 2009 (45)400-404 

B. Karlovits et al  Stereotactic Radiosurgery Boost to the Resection Bed for Oligometastatic Brain Disease: Challenging the Tradition of Adjuvant Whole-Brain Radiotherapy  Neurosurgery Focus Dec 2009 27(6)

P.Tolentino   Brain Metastases Secondary to Breast Cancer: Treatment with Surgical Resection and Stereotactic Radiosurgery  Mo Med Nov-Dec 2009 106(6):428-31

J. Wong et al  Symptoms and Quality of Life in Cancer Patients with Brain Metastases Following Palliative Radiotherapy  International Journal of Radiation Oncology Biology Physics Nov 25 2009 75(4):1125-31

J. Samblas et al  Radiosurgery and Whole Brain Therapy in the Treatment of Brainstem Metastases Oct 2009 11(10):677-80

Jagannathan et al  Gamma Knife Radiosurgery to the Surgical Cavity Following Resection of Brain Metastases J Neurosurg Sept 2009 11(3):431-8

S. Yoshida, H. Takahashi, Cerebellar metastases in patients with cancer Surgical Neurology. 2008 Feb 22

A. Pompili, C. Carapella, A. Pace et al. Metastases to the Cerebellum, Results and Prognostic Factors in a Consecutive Series of 44 Operated Patients   Journal of Neurooncology, 2008;(88):331-337

C. Nieder, K. Marienhagen, J.Norum, et al Prediction of Very Short Survival in Patients with Brain Metastases from   Breast Cancer Clinical Oncology, 2008; (20): 337-339

M. Hemphill and J. Lawrence. Current Therapeutic Options for Breast Cancer Central Nervous System Metastases  Current Treatment, Options in Oncology, 2008; (9): 41-50

N. Kased, K. Huang, P. Sneed, et al  Gamma Knife Radiosurgery for Brainstem Metastases: the UCSF Experience   Journal of Neurooncology,2008; 886:195-205

C. Nieder, S.T. Astner, A. Grosu, N. H. Andratschke, M.Molls.The Role of Postoperative Radiotherapy after Resection of a Single Brain Metastasis: Combined Analysis of 643 Patients. Strahlenther Onkol 2007;183:576–80

D. Rades, A. Pluemer, T. Veninga et al A Boost in Addition to Whole-Brain Radiotherapy Improves Patient Outcome after Resection of 1 or 2 Brain metastases in Recursive Partitioning Analysis Class 1 and 2 Patients Cancer, October 1, 2007; 110 (7): 1551-1559.

M. Ranasinghe and J. Sheehan Surgical Management and Brain Metastases Neurosurgery Focus, March 2007;  22 (3): 1-7.

E. Chang, J. Wefel, M. Maor et al A Pilot Study of Neurocognitive Function in Patients with One to Three New Brain Metastases Initially Treated with Stereotactic Radiosurgery Alone Neurosurgery, February 2007; 60 (2): 277-284.

C.P. Yen, J. Sheehan, G. Patterson and L. Steiner Gamma Knife surgery for metastatic brainstem tumors Journal of Neurosurgery 105:213–219, 200

H. Stemmler, M. Schmitt, N. Harbeck et al Application of Intrathecal Trastuzumab (Herceptin) for Treatment of Meningeal Carcinomatosis in Her-2 Overexpressing Metastatic Breast Cancer   Oncology Reports, 2006; 15: 1373-77 

A. Ghia, W. Tome, M. Mehta et al Distribution of Brain Metastases in Relation to the Hippocampus: Implications for Neurocognitive Functional Preservation, International Journal of Radiation Oncology Biology Physics, 2007; 64 (40): 971-977 

E. Sadikov, A. Bezjak, N. Laperriere et al Value of Whole Brain Re-irradiation for Brain Metastases-Single Centre Experience   Clinical Oncology, 2007; (19): 532-538 

T. Nguyen and L. Abrey. Brain Metastases: Old Problem, New Strategies Hematology/Oncology Clinics of North America, April 2007; (21): 369-388 
M. Smith and J. Lee. Stereotactic Radiosurgery in the Management of Brain Metastasis, Neurosurgery Focus, 2007; 22 (3): E5

C. Nieder, S. Astner. and M. Molls. The Role of Postoperative Radiotherapy After Resection of a Single Brain Metastasis   .Strahlenther und Onkologie,  2007; 576-580 (English)

H. Aoyama, H. Shirato, M. Tago et al Stereotactic Radiosurgery Plus Whole-Brain Radiation Therapy vs Stereotactic Radiosurgery Alone for Treatment of Brain Metastases  The Journal of the American Medical Association, June 7, 2006; 295 (21): 2483-2491.

J. Raizer Editorial: Radiosurgery and Whole-Brain Radiation Therapy for Brain Metastases-Either or Both as the Optimal Treatment The Journal of the American Medical Association, June 7, 2006; 295 (21).

L. R Kleinberg, J. Wefel, W. Regine Should Whole Brain Radiation Therapy Follow Focal Therapy of a Single and Multiple Brain Metastasis?   2006 ASCO Education Session (4 presentations, with audio and slides).

R. Bartsch, S. Fromm, M. Rudas et al Intensified local treatment and Systemic Therapy Significantly Increase Survival in Patients with Brain Metastases from Advanced Breast Cancer-A Retrospecitive Analysis Radiotherapy and Oncology; 2006; 80: 313-317.

D. Andrews, C Scott, P. Sperduto et al Whole Brain Radiation Therapy With or Without Stereotatic Radiosurgery Boost for Patients with One to Three Brain Metastases: Phase III Results of the RTOG 9508 Randomised Trial The Lancet, May 22, 2004; 363: 1665.

D. Rades, A. Rabbe, A. Barjrovic et al Treatment of Solitary Brain Metastasis Resection Followed by Whole Brain Radiation Therapy (WBRT) and a Radiation Boost to the Metastatic Site Strahlenther Onkol, 2004; 180: 144-147.

P. Sperduto A Review of Stereotactic Radiosurgery in the Management of Brain Metastases Technology in Cancer Research and Treatment, April 2003; 2(3): 105-109.

K. Firlik, D. Kondziolka, J. Flickinger et al Stereotactic Radiosurgery for Brain Metastases from Breast Cancer Annals of Surgery Oncology, 2000; 7 (5): 333-338  (free full text).

J. Rock, S. Haines, L. Recht et al Practice Parameters for the Management of Single Brain Metastasis Neurosurgery Focus, December 2000; 9 (6): 1-9 (free full text).

R. Patchell, P. Tibbs, J. Walsh et al A Randomized Trial of Surgery in the Treatment of Single Metastases to the Brain The New England Journal of Medicine, February 22, 1999; 322 (8): 494-500.

R. Crossen, D. Garwood, E. Neuwelt Neurobehavioral Sequelae of Cranial Irradiation in Adults: A Review of Radiation-Induced Encephalopathy Journal of Clinical Oncology, March 1994; 12 (3): 627-622.