Research on Trastuzumab for Leptomengeal Metastases

Debra Schwab Brandt  Intrathecal Trastuzumab (Herceptin): 46 Months and No progression  Community Oncology July 2012  

 M. Oliviera et al  Complete Response in HER2+ Leptomeningeal Carcinomatosis from Breast Cancer with Intrathecal Trastuzumab (Herceptin)  Breast Cancer Research and Treatment 2011 (127):841-844 

 C. Dumitrescu D. Lossignal  Intrathecal Trastuzumab( Herceptin) Treatment of The Neoplastic Meningitis Due To Breast Cancer: A Case Report and Review of the Literature  Jules Bordet Institute   

M. Chamberlain  Leptomeningeal Metastasis  Seminars in Neurology  Jul 2010 30(30):236-44 

A. Perissinotti D. Reeves  Role of Intrathecal Rituzumab and Trastuzumab (Herceptin) in the Management of Leptomeningeal Carcinomatosis  The Annals of Pharmacotherapy  2010 Oct.10 Volume 44 1633-39

C. Ferrario  A. Davidson  et al  Intrathecal Trastuzumab and Thiotepa for Leptomeningeal Trastuzumab (Herceptin) and Thiotepa for Leptomeningeal Spread of Breast Cancer  Ann Oncol 20(4):792-795, 2009

T Shigekawa H Takeuchi et al  Successful Treatment of Leptomeningeal Metastases from Breast Cancer Using the Combination of Trastuzumab (Herceptin) and Capecitabine (Xeloda): A Case Report.  Breast Cancer 2009 16:88-92 

Yen-Hsun Chen  Wei-Shiou Hwang et al  Case Report: Intrathecal Trastuzumab (Herceptin) for Meningeal Carcinomatosis Secondary to Her1-overexpressing Breast Cancer   Journal of Chinese Oncology Society 25(5) 357-364 2009

O. Mir et al  High-Dose Intrathecal Trastuzumab (Herceptin) for Leptomeningel Metastases Secondary to Her-2 Overexpressing Breast Cancer  Ann Oncol Nov 2008 19(11):1978-80

H. Stemmler K. Mengele  M. Schmitt  et al  Intrathecal Trastuzumab (Herceptin) and Methotrexate for Meningeal Carcinomatosis in HER2-overexpressing Metastatic Breast Cancer: A Case Report  Anticancer Drugs 19: 832-836 2008

H. Stemmler M. Schmitt  N. Harbeck et al  Application of Intrathecal Trastuzumab (Herceptin) for Treatment of Meningeal Carcinomatosis in HER2-Overexpressing Metastatic Breast Cancer  Oncology Reports  2006; 15: 1373-1377

C. Platini  J. Long S. Walter et al  Meningeal Carcinomatosis from Breast Cancer Treated with Intrathecal Trastuzumab (Herceptin)  Lancet Oncol 7: 778-780 2006

LR Laufman  KF Forsthoefel  Use of Intrathecal Trastuzumab (Herceptin) in a Patient with Carcinomatous Meningitis  Clin Breast Cancer 2: 235  2001

RH Baculi S Suki J Nisbett J, et al  Meningeal Carcinomatosis from Breast Carcinoma Responsiveto Trastuzumab (Herceptin)  J Clin Oncol 19: 3297-3298  2001